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Diferenciální exprese transkriptů slinných žláz klíštěte \kur{Ixodes ricinus}
 KROPÁČKOVÁ, Sára
Ticks are using different mechanisms for host immune system suppression. In this thesis, I compared ten transcripts from ticks salivary glands, which are differentially expressed during feeding on live animal and artificial systems. Further, a tick protein anticomplement 1, AC1, was chosen and subjected to deeper investigation, because of the significant difference in expression during feeding. Serum with specific antibodies was made and AC1 expression levels were examined in nymphs and adults, during feeding on different hosts. Moreover, any potential interacting partners from host serum through covalent binding were tested. This study contributes to the understanding of regulation of expression and funtional characterisation of tick salivary proteins.
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